Junctophilin 2 antibody (AA 625-675)

Catalog No. ABIN7450382

The Rabbit Polyclonal anti-Junctophilin 2 antibody has been validated for WB and IP. It is suitable to detect Junctophilin 2 in samples from Human.

Quick Overview for Junctophilin 2 antibody (AA 625-675) (ABIN7450382)

Target: Junctophilin 2 (JPH2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Junctophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Junctophilin 2 Antibody

Binding Specificity: AA 625-675

Purpose: Rabbit anti-Junctophilin-2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 625 and 675

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Junctophilin 2

Target: Junctophilin 2 (JPH2)

Alternative Name: Junctophilin-2

Background: Background: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Junctophilins provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. Junctophilin-2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release, and contributes to the construction of skeletal muscle triad junctions [taken from the Universal Protein Resource (UniProt) Q9BR39].

Gene ID: 57158

NCBI Accession: NP_065166

UniProt: Q9BR39