MAP4K4 antibody (AA 850-900)
Quick Overview for MAP4K4 antibody (AA 850-900) (ABIN7450432)
Target
See all MAP4K4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 850-900
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Purpose
- Rabbit anti-MAP4K4/HGK Antibody, Affinity Purified
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Predicted Reactivity
- Mouse
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Purification
- Affinity Purified
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Immunogen
- between AA 850 and 900
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Isotype
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibody
MAP4K4 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 4A5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 866-1104) antibodyMAP4K4 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 400-500) antibodyMAP4K4 Reactivity: Human ELISA Host: Mouse Monoclonal 4H9E7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 287-336) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Bat, Chicken, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) antibodyMAP4K4 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 25GB1895 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse, Rat WB, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (N-Term) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 550-600) antibodyMAP4K4 Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Alternative Name
- MAP4K4/HGK
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Background
- Background: MAP4K4 is a serine/threonine kinase that signals upstream of the c-Jun N-terminal kinase (JNK) and is involved in cell motility. MAP4K4 appears to partially mediate TNF alpha signaling. In skeletal muscle TNF-alpha induces insulin resistance. TNF-alpha induced insulin resistance has been shown to be dependent on MAPK4K4 activity. Interestingly, TNF-alpha regulates MAP4K4 expression and can stimulate MAP4K4 gene expression via TNFR2 (TNFalpha receptor 2) and the c-Jun and ATF2 (activating transcription factor 2) transcription factors. MAP4K4 is highly expressed in most tumor cell lines, and the analysis of MAP4K4 mutants indicates that it may have an important role in cell transformation and invasiveness.
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Gene ID
- 9448
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UniProt
- O95819
Target
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