MCMBP antibody (AA 150-200)
Quick Overview for MCMBP antibody (AA 150-200) (ABIN7450436)
Target
See all MCMBP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 150-200
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Purpose
- Rabbit anti-MCM-BP Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 150 and 200
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))
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Alternative Name
- MCM-BP
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Background
- Background: MCM-binding protein is an associated component of the MCM (mini-chromosome maintenance) complex that acts as a regulator of DNA replication. MCM-BP binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. MCM-BP is required for sister chromatid cohesion [taken from the Universal Protein Resource (UniProt) Q9BTE3].
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Gene ID
- 79892
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NCBI Accession
- NP_079110
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UniProt
- Q9BTE3
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Pathways
- Chromatin Binding
Target
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