MUM1 antibody (AA 125-175)

Catalog No. ABIN7450469

The Rabbit Polyclonal anti-MUM1 antibody has been validated for WB and IP. It is suitable to detect MUM1 in samples from Human.

Quick Overview for MUM1 antibody (AA 125-175) (ABIN7450469)

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MUM1 Antibody

Binding Specificity: AA 125-175

Purpose: Rabbit anti-MUM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Alternative Name: MUM1

Background: Background: Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. MUM1 is required for efficient DNA repair and cell survival following DNA damage [taken from the Universal Protein Resource (UniProt) Q2TAK8].

Gene ID: 84939

NCBI Accession: NP_116242

UniProt: Q2TAK8

Pathways: Chromatin Binding