NXF1 antibody (AA 569-619)

Catalog No. ABIN7450520

The Rabbit Polyclonal anti-NXF1 antibody is suitable to detect NXF1 in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for NXF1 antibody (AA 569-619) (ABIN7450520)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NXF1 Antibody

Binding Specificity: AA 569-619

Purpose: Rabbit anti-NXF1 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 569 and 619

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Alternative Name: NXF1

Background: Background: Nuclear RNA export factor 1 (NXF1) is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p [taken from NCBI Entrez Gene (Gene ID: 10482)].

Gene ID: 10482

NCBI Accession: NP_006353

UniProt: Q9UBU9