PAK4 antibody (AA 25-75)

Catalog No. ABIN7450536

This anti-PAK4 antibody is a Rabbit Polyclonal antibody detecting PAK4 in WB and IP. Suitable for Human and Mouse.

Quick Overview for PAK4 antibody (AA 25-75) (ABIN7450536)

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PAK4 Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-PAK4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Alternative Name: PAK4

Background: Background: PAK4 is a member of the PAK family of serine/threonine p21-activating kinases. PAK4 is a target for the GTP-bound Rho GTPase, CDC42, and is an important factor that links Rho GTPases such as Ras to transformation. In this context, PAK4 is highly transforming, and has been found to be highly expressed in some tumor cell lines. PAK4 has been demonstrated to activate the JNK pathway and mediate the formation of filopodia and the reorganization of the actin cytoskeleton. PAK4 has also been found to function as a regulator of prosurvival pathways and senescence.

Gene ID: 10298

NCBI Accession: NP_005875

UniProt: O96013

Pathways: RTK Signaling