PAPD1 antibody (AA 532-582)

Catalog No. ABIN7450541

Product Details anti-PAPD1 Antibody

Target: PAPD1 (MTPAP) (Mitochondrial Poly(A) Polymerase (MTPAP))

Binding Specificity: AA 532-582

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-PAPD1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 532 and 582

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAPD1

Target: PAPD1 (MTPAP) (Mitochondrial Poly(A) Polymerase (MTPAP))

Alternative Name: PAPD1 (MTPAP Products)

Synonyms: PAPD1 antibody, SPAX4 antibody, 0610027A18Rik antibody, AW551379 antibody, Papd1 antibody, mitochondrial poly(A) polymerase antibody, MTPAP antibody, Mtpap antibody

Background: Background: PAPD1 (mitochondrial poly(A) polymerase) is a polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. PAPD1 can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). It plays a role in replication-dependent histone mRNA degradation. It may be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated and might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA [taken from NCBI Entrez Gene (Gene ID: 55149)].

Gene ID: 55149

NCBI Accession: NP_060579

UniProt: Q9NVV4