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RAPTOR antibody (AA 1-50)

This Rabbit Polyclonal antibody specifically detects RAPTOR in WB and IP. It exhibits reactivity toward Human.
Catalog No. ABIN7450636

Quick Overview for RAPTOR antibody (AA 1-50) (ABIN7450636)

Target

See all RAPTOR Antibodies
RAPTOR

Reactivity

  • 52
  • 45
  • 25
  • 15
  • 1
  • 1
Human

Host

  • 53
  • 3
Rabbit

Clonality

  • 52
  • 4
Polyclonal

Conjugate

  • 21
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RAPTOR antibody is un-conjugated

Application

  • 30
  • 26
  • 26
  • 17
  • 7
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

    • 15
    • 15
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    Purpose

    Rabbit anti-Raptor Antibody, Affinity Purified

    Purification

    Affinity Purified

    Immunogen

    between AA 1 and 50

    Isotype

    IgG
  • Application Notes

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    RAPTOR

    Alternative Name

    Raptor

    Background

    Background: Raptor (regulatory-associated protein of mTOR) is part of the rapamycin sensitive mTORC1 complex which includes mTOR, and mLst8/GbetaL. S6K and 4EBP1 are substrates of mTORC1 kinase activity. Raptor is required for mTOR's ability to phosphorylate 4E-BP1 and physically interacts with 4EBP1 to act as a potential scaffold that bridges mTOR and 4EBP1 or S6K. The mTORC1 complex integrates cell signals to promote cell growth in response to growth factors.

    Gene ID

    57521

    UniProt

    Q8N122

    Pathways

    Warburg Effect
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