RAPTOR antibody (AA 1-50)
Quick Overview for RAPTOR antibody (AA 1-50) (ABIN7450636)
Target
See all RAPTOR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Rabbit anti-Raptor Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- RAPTOR
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Alternative Name
- Raptor
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Background
- Background: Raptor (regulatory-associated protein of mTOR) is part of the rapamycin sensitive mTORC1 complex which includes mTOR, and mLst8/GbetaL. S6K and 4EBP1 are substrates of mTORC1 kinase activity. Raptor is required for mTOR's ability to phosphorylate 4E-BP1 and physically interacts with 4EBP1 to act as a potential scaffold that bridges mTOR and 4EBP1 or S6K. The mTORC1 complex integrates cell signals to promote cell growth in response to growth factors.
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Gene ID
- 57521
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UniProt
- Q8N122
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Pathways
- Warburg Effect
Target
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