RBBP6 antibody (AA 50-100)

Catalog No. ABIN7450638

This anti-RBBP6 antibody is a Rabbit Polyclonal antibody detecting RBBP6 in WB and IP. Suitable for Human.

Quick Overview for RBBP6 antibody (AA 50-100) (ABIN7450638)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RBBP6 Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-RBBP6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RBBP6

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: RBBP6

Background: Background: Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) Q7Z6E9].

Gene ID: 5930

UniProt: Q7Z6E9

Pathways: Regulatory RNA Pathways