RPS24 antibody (AA 83-133)

Catalog No. ABIN7450691

Product Details anti-RPS24 Antibody

Target: RPS24 (Ribosomal Protein S24 (RPS24))

Binding Specificity: AA 83-133

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS24 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-RPS24 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Golden hamster

Purification: Affinity Purified

Immunogen: Between AA 83 and 133

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RPS24

Target: RPS24 (Ribosomal Protein S24 (RPS24))

Alternative Name: RPS24 (RPS24 Products)

Synonyms: DBA3 antibody, S24 antibody, ribosomal protein S24 L homeolog antibody, ribosomal protein S24 antibody, rps24.L antibody, RPS24 antibody, Rps24 antibody

Background: Background: RPS24 (40S ribosomal protein S24) is a component of the 40S ribosomal subunit required for the processesing of pre-rRNA and maturation of the 40S ribosomal subunits. Defects in the RPS24 gene are the cause of Diamond-Blackfan anemia type 3 (DBA3) [MIM:610629]. DBA3 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40 % of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies [taken from the Universal Protein Resource (UniProt) P62847].

Gene ID: 6229

NCBI Accession: NP_001017

UniProt: P62847