ZFYVE9 antibody (AA 1-50)

Catalog No. ABIN7450706

Product Details anti-ZFYVE9 Antibody

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE9 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SARA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ZFYVE9

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Alternative Name: SARA (ZFYVE9 Products)

Background: Background: Smad anchor for receptor activation (SARA) is an early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization [taken from the Universal Protein Resource (UniProt) O95405].

Gene ID: 9372

NCBI Accession: NP_004790

UniProt: O95405

Pathways: Protein targeting to Nucleus