ZFYVE9 antibody (AA 1-50)
Quick Overview for ZFYVE9 antibody (AA 1-50) (ABIN7450706)
Target
See all ZFYVE9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Rabbit anti-SARA Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))
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Alternative Name
- SARA
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Background
- Background: Smad anchor for receptor activation (SARA) is an early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization [taken from the Universal Protein Resource (UniProt) O95405].
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Gene ID
- 9372
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NCBI Accession
- NP_004790
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UniProt
- O95405
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Pathways
- Protein targeting to Nucleus
Target
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