SEC62 antibody (AA 349-399)

Catalog No. ABIN7450714

This Rabbit Polyclonal antibody specifically detects SEC62 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for SEC62 antibody (AA 349-399) (ABIN7450714)

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SEC62 Antibody

Binding Specificity: AA 349-399

Purpose: Rabbit anti-Sec62 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 349 and 399

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: Sec62

Background: Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Sec62 and Sec63 protein are found to be associated with ribosome-free Sec61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Sec62 is an integral membrane protein located in the rough ER [taken from NCBI Entrez Gene (Gene ID: 7095)].

Gene ID: 7095

NCBI Accession: NP_003253

UniProt: Q99442