SMARCAD1 antibody (AA 976-1026)

Catalog No. ABIN7450747

This Rabbit Polyclonal antibody specifically detects SMARCAD1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SMARCAD1 antibody (AA 976-1026) (ABIN7450747)

Target: SMARCAD1 (SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCAD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SMARCAD1 Antibody

Binding Specificity: AA 976-1026

Purpose: Rabbit anti-SMARCAD1/ETL1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 976 and 1026

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMARCAD1

Target: SMARCAD1 (SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1))

Alternative Name: SMARCAD1/ETL1

Background: Background: The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.

Gene ID: 56916

NCBI Accession: NP_064544

UniProt: Q9H4L7