SMARCAD1 antibody (Internal Region)
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- Target See all SMARCAD1 Antibodies
- SMARCAD1 (SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMARCAD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- SMARCAD1 Antibody detects endogenous levels of total SMARCAD1.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SMARCAD1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SMARCAD1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- SMARCAD1 (SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1))
- Alternative Name
- SMARCAD1 (SMARCAD1 Products)
- Synonyms
- etl1 antibody, DKFZp468C0919 antibody, smarcad1a antibody, wu:fi25c01 antibody, zgc:113183 antibody, ADERM antibody, ETL1 antibody, HEL1 antibody, AV081750 antibody, AW226546 antibody, D6Pas1 antibody, Etl1 antibody, mKIAA1122 antibody, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 antibody, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 S homeolog antibody, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a antibody, SMARCAD1 antibody, smarcad1.S antibody, smarcad1 antibody, smarcad1a antibody, Smarcad1 antibody
- Background
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Description: DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing.
Gene: SMARCAD1
- Molecular Weight
- 117 kDa
- Gene ID
- 56916
- UniProt
- Q9H4L7
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