TAF1 antibody (AA 1800-1850)
Quick Overview for TAF1 antibody (AA 1800-1850) (ABIN7450798)
Target
See all TAF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1800-1850
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Purpose
- Rabbit anti-TAF1 Antibody, Affinity Purified
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Predicted Reactivity
- Golden hamster
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Purification
- Affinity Purified
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Immunogen
- between AA 1800 and 1850
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
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Alternative Name
- TAF1
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Background
- Background: Transcription initiation factor TFIID subunit 1 (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex. TAF1 contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. It also phosphorylates GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) P21675].
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Gene ID
- 6872
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NCBI Accession
- NP_620278
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UniProt
- P21675
Target
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