UBA6 antibody (AA 1002-1052)

Catalog No. ABIN7450859

The Rabbit Polyclonal anti-UBA6 antibody has been validated for WB and IP. It is suitable to detect UBA6 in samples from Human.

Quick Overview for UBA6 antibody (AA 1002-1052) (ABIN7450859)

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-UBA6 Antibody

Binding Specificity: AA 1002-1052

Purpose: Rabbit anti-UBA6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1002 and 1052

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UBA6

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Alternative Name: UBA6

Background: Background: Ubiquitin-like modifier-activating enzyme 6 (UBA6) activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. UBA6 is specific for ubiquitin and does not activate ubiquitin-like peptides. UBA6 differs from UBE1 in its specificity for substrate E2 charging. UBA6 does not charge cell cycle E2s, such as CDC34. UBE6 is essential for embryonic development and required for UBD/FAT10 conjugation [taken from the Universal Protein Resource (UniProt) A0AVT1].

Gene ID: 55236

NCBI Accession: NP_060697

UniProt: A0AVT1