VTA1 antibody (AA 250-300)

Catalog No. ABIN7450903

Product Details anti-VTA1 Antibody

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Binding Specificity: AA 250-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 250 and 300

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1/LIP5 (VTA1 Products)

Synonyms: C6orf55 antibody, DRG-1 antibody, DRG1 antibody, LIP5 antibody, My012 antibody, SBP1 antibody, 1110001D18Rik antibody, 1110059P08Rik antibody, AU040813 antibody, C85340 antibody, Lip5 antibody, RGD1305031 antibody, Vps20-associated 1 homolog antibody, vesicle trafficking 1 antibody, vesicle (multivesicular body) trafficking 1 antibody, Vta1 antibody, VTA1 antibody

Background: Background: VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) Q9NP79].

Gene ID: 51534

UniProt: Q9NP79