EZH2 antibody (AA 696-746)

Catalog No. ABIN7450991

The Rabbit Polyclonal anti-EZH2 antibody has been validated for WB and IP. It is suitable to detect EZH2 in samples from Human and Mouse.

Quick Overview for EZH2 antibody (AA 696-746) (ABIN7450991)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EZH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-EZH2 Antibody

Binding Specificity: AA 696-746

Purpose: Rabbit anti-EZH2 Antibody, Affinity Purified

Predicted Reactivity: Zebrafish,X. laevis,X. tropicalis

Purification: Affinity Purified

Immunogen: Between AA 696 and 746

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Alternative Name: EZH2

Background: Background: Enhancer of zeste homolog 2 (EZH2) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems [taken from NCBI Entrez Gene (Gene ID: 2146)].

Gene ID: 2146

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation