PDCD10 antibody (AA 75-125)

Catalog No. ABIN7451085

This anti-PDCD10 antibody is a Rabbit Polyclonal antibody detecting PDCD10 in IP. Suitable for Human.

Quick Overview for PDCD10 antibody (AA 75-125) (ABIN7451085)

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD10 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-PDCD10 Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-PDCD10/CCM3 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken

Purification: Affinity Purified

Immunogen: Between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451085 has not performed satisfactorily when used for WB of PDCD10/CCM3 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PDCD10/CCM3.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PDCD10

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Alternative Name: PDCD10/CCM3

Background: Background: PDCD10 is an evolutionarily conserved protein associated with cell apoptosis. PDCD10 interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent [taken from NCBI Entrez Gene (Gene ID: 11235)].

Gene ID: 11235

NCBI Accession: NP_665859

UniProt: Q9BUL8