FGD1 antibody (AA 50-100)

Catalog No. ABIN7451132

The Rabbit Polyclonal anti-FGD1 antibody has been validated for IP. It is suitable to detect FGD1 in samples from Human.

Quick Overview for FGD1 antibody (AA 50-100) (ABIN7451132)

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FGD1 Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-FGD1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451132 has not performed satisfactorily when used for WB of FGD1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of FGD1.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FGD1

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Alternative Name: FGD1

Background: Background: The gene FGD1 encodes for FYVE, RhoGEF and PH domain-containing protein 1. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16 [taken from NCBI Entrez Gene (Gene ID: 2245)].

Gene ID: 2245

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway