IRS4 antibody (AA 875-925)

Catalog No. ABIN7451152

This Rabbit Polyclonal antibody specifically detects IRS4 in IP. It exhibits reactivity toward Human.

Quick Overview for IRS4 antibody (AA 875-925) (ABIN7451152)

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS4 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-IRS4 Antibody

Binding Specificity: AA 875-925

Purpose: Rabbit anti-IRS4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 875 and 925

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451152 has not performed satisfactorily when used for WB of IRS4 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of IRS4.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IRS4

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Alternative Name: IRS4

Background: Background: Insulin receptor substrate 4 (IRS4) is a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation [taken from NCBI Entrez Gene (Gene ID: 8471)].

Gene ID: 8471

UniProt: O14654