MPI antibody (AA 25-75)

Catalog No. ABIN7451179

Product Details anti-MPI Antibody

Target: MPI (Mannose Phosphate Isomerase (MPI))

Binding Specificity: AA 25-75

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPI antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-MPI Antibody, Affinity Purified

Predicted Reactivity: Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451179 has not performed satisfactorily when used for WB of MPI in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MPI.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MPI

Target: MPI (Mannose Phosphate Isomerase (MPI))

Alternative Name: MPI (MPI Products)

Synonyms: CDG1B antibody, PMI antibody, PMI1 antibody, 1110002E17Rik antibody, AI315153 antibody, Mpi-1 antibody, Mpi1 antibody, im:7140016 antibody, zgc:110773 antibody, cdg1b antibody, pmi antibody, pmi1 antibody, CaO19.1390 antibody, mannose phosphate isomerase antibody, mannose phosphate isomerase S homeolog antibody, mannose phosphate isomerase (mapped) antibody, mannose-6-phosphate isomerase antibody, MPI antibody, Mpi antibody, mpi antibody, mpi.S antibody, PMI1 antibody

Background: Background: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants [taken from NCBI Entrez Gene (Gene ID: 4351)].

Gene ID: 4351

UniProt: P34949