BCOR antibody (AA 25-75)

Catalog No. ABIN7451200

This Rabbit Polyclonal antibody specifically detects BCOR in IP. It exhibits reactivity toward Human.

Quick Overview for BCOR antibody (AA 25-75) (ABIN7451200)

Target: BCOR (BCL6 Co-Repressor (BCOR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCOR antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-BCOR Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-BCoR Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-BCoR antibody ABIN7451662.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCOR

Target: BCOR (BCL6 Co-Repressor (BCOR))

Alternative Name: BCoR

Background: Background: The BCL6 co-repressor (BCOR) was identified in a two-hybrid screen for factors that interact with the POZ domain of BCL6, a transcriptional repressor important to the immune response and B-cell development. BCOR also interacts with class I and II histone deacetylases and has recently been identified in a complexes with polycomb group proteins, RING1, RYBP, SNSC1, and RNF2, and the ubiquitin E3 ligase SKP1, and JHDM1B. Defects in BCOR are associated with oculo-facio-cardio-dental (OFCD) syndrome, a rare X-linked dominant disease that is fatal in males.

Gene ID: 54880

UniProt: Q6W2J9