Calpastatin antibody (AA 425-475)

Catalog No. ABIN7451204

The Rabbit Polyclonal anti-Calpastatin antibody has been validated for IP. It is suitable to detect Calpastatin in samples from Human.

Quick Overview for Calpastatin antibody (AA 425-475) (ABIN7451204)

Target: Calpastatin (CAST)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpastatin antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-Calpastatin Antibody

Binding Specificity: AA 425-475

Purpose: Rabbit anti-Calpastatin/CAST Antibody, Affinity Purified

Predicted Reactivity: Sheep,Pig

Purification: Affinity Purified

Immunogen: Between AA 425 and 475

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-Calpastatin/CAST antibody ABIN7450058 or ABIN7450059.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Calpastatin

Target: Calpastatin (CAST)

Alternative Name: Calpastatin/CAST

Background: Background: Calpastatin is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation [taken from NCBI Entrez Gene (Gene ID: 831)].

Gene ID: 831

NCBI Accession: NP_001035908

UniProt: P20810