G3BP2 antibody (AA 432-482)

Catalog No. ABIN7451249

The Rabbit Polyclonal anti-G3BP2 antibody has been validated for IP. It is suitable to detect G3BP2 in samples from Human.

Quick Overview for G3BP2 antibody (AA 432-482) (ABIN7451249)

Target: G3BP2 (GTPase Activating Protein (SH3 Domain) Binding Protein 2 (G3BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G3BP2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-G3BP2 Antibody

Binding Specificity: AA 432-482

Purpose: Rabbit anti-G3BP2 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan

Purification: Affinity Purified

Immunogen: between AA 432 and 482

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-G3BP2 antibody ABIN7449882.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for G3BP2

Target: G3BP2 (GTPase Activating Protein (SH3 Domain) Binding Protein 2 (G3BP2))

Alternative Name: G3BP2

Background: Background: Ras-GAP SH3 domain binding protein (G3BP2) contains an RNA recognition motif (RRM) and an N-terminal nuclear transport factor 2-like (NTF2-like) domain. The G3BP family of proteins have been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation.G3BP2 can interact with IkappaBalpha and IkappaBalpha/NFkappaB complexes. In this complex G3B2 is proposed to play a role in regulating the nucleocytoplasmic localization of NFkappaB as well as its activity.

Gene ID: 9908

NCBI Accession: NP_036429

UniProt: Q9UN86

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome