MPP5 antibody (AA 225-275)

Catalog No. ABIN7451275

This Rabbit Polyclonal antibody specifically detects MPP5 in IP. It exhibits reactivity toward Human.

Quick Overview for MPP5 antibody (AA 225-275) (ABIN7451275)

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-MPP5 Antibody

Binding Specificity: AA 225-275

Purpose: Rabbit anti-MPP5/Pals1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-MPP5/Pals1 antibody ABIN7450460.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MPP5

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Alternative Name: MPP5/Pals1

Background: Background: Membrane palmitoylated protein 5 (MPP5) is a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. MPP5 participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289) [taken from NCBI Entrez Gene (Gene ID: 64398)].

Gene ID: 64398

UniProt: Q8N3R9

Pathways: Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization