PFKL antibody (AA 730-780)

Catalog No. ABIN7451300

The Rabbit Polyclonal anti-PFKL antibody has been validated for IP. It is suitable to detect PFKL in samples from Human.

Quick Overview for PFKL antibody (AA 730-780) (ABIN7451300)

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKL antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-PFKL Antibody

Binding Specificity: AA 730-780

Purpose: Rabbit anti-PFKL Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 730 and 780

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-PFKL antibody ABIN7449786.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Alternative Name: PFKL

Background: Background: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. PFKL represents the L subunit [taken from the Universal Protein Resource (UniProt) P17858].

Gene ID: 5211

NCBI Accession: NP_002617

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, Warburg Effect