PRMT5 antibody (AA 50-100)

Catalog No. ABIN7451315

The Rabbit Polyclonal anti-PRMT5 antibody has been validated for IP. It is suitable to detect PRMT5 in samples from Human.

Quick Overview for PRMT5 antibody (AA 50-100) (ABIN7451315)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-PRMT5 Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-PRMT5 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-PRMT5 antibody ABIN7453831.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Alternative Name: PRMT5

Background: Background: Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.

Gene ID: 10419

NCBI Accession: NP_006100

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development