TJP3 antibody (AA 325-375)

Catalog No. ABIN7451362

This Rabbit Polyclonal antibody specifically detects TJP3 in IP. It exhibits reactivity toward Human.

Quick Overview for TJP3 antibody (AA 325-375) (ABIN7451362)

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP3 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-TJP3 Antibody

Binding Specificity: AA 325-375

Purpose: Rabbit anti-TJP3/ZO-3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 325 and 375

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-TJP3/ZO-3 antibody A304-926A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TJP3

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Alternative Name: TJP3/ZO-3

Background: Background: Tight junction protein 3 (TJP3) is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. TJP3 plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis [taken from NCBI Entrez Gene (Gene ID: 27134)].

Gene ID: 27134

UniProt: O95049