Multidrug-Resistance Like Protein 1 antibody (AA 275-325)
Quick Overview for Multidrug-Resistance Like Protein 1 antibody (AA 275-325) (ABIN7451476)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 275-325
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Purpose
- Rabbit anti-MRP1 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 275 and 325
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Isotype
- IgG
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anti-Multidrug-Resistance Like Protein 1 (MRP) (AA 501-600) antibody
MRP Reactivity: Human, Rat WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Multidrug-Resistance Like Protein 1 (MRP) antibodyMRP Reactivity: Human, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- Multidrug-Resistance Like Protein 1 (MRP)
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Alternative Name
- MRP1
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Background
- Background: Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. MRP1 functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. MRP1 also transports glucuronides and sulfate conjugates of steroid hormones and bile salts [taken from NCBI Entrez Gene (Gene ID: 4363)].
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Gene ID
- 4363
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NCBI Accession
- NP_004987
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UniProt
- P33527
Target
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