RGS14 antibody (AA 1-50)

Catalog No. ABIN7451502

The Rabbit Polyclonal anti-RGS14 antibody (ABIN7451502) specifically detects RGS14 in IP. The antibody is reactive with Human samples.

Quick Overview for RGS14 antibody (AA 1-50) (ABIN7451502)

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS14 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-RGS14 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-RGS14 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Alternative Name: RGS14

Background: Background: Regulator of G-protein signaling 14 (RGS14) acts as a regulator of G protein signaling (RGS). Modulates G protein alpha subunits nucleotide exchange and hydrolysis activities by functioning either as a GTPase-activating protein (GAP), thereby driving G protein alpha subunits into their inactive GDP-bound form, or as a GDP-dissociation inhibitor (GDI). RGS14 may act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways [taken from the Universal Protein Resource (UniProt) O43566].

Gene ID: 10636

NCBI Accession: NP_006471

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling