TIMM8A/DDP antibody (AA 1-50)

Catalog No. ABIN7451527

This Rabbit Polyclonal antibody specifically detects TIMM8A/DDP in IP. It exhibits reactivity toward Human.

Quick Overview for TIMM8A/DDP antibody (AA 1-50) (ABIN7451527)

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM8A/DDP antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-TIMM8A/DDP Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-TIMM8A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TIMM8A/DDP

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Alternative Name: TIMM8A

Background: Background: Translocase of inner mitochondrial membrane 8 homolog A (TIMM8A) is a translocase involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The TIMM8A gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS), and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in the TIMM8A gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. Along with TIMM13, TIMM8A forms a 70 kDa heterohexamer [taken from NCBI Entrez Gene (Gene ID: 1678)].

Gene ID: 1678

NCBI Accession: NP_004076

UniProt: O60220