APC1 antibody (AA 500-550)

Catalog No. ABIN7451635

This Rabbit Polyclonal antibody specifically detects APC1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for APC1 antibody (AA 500-550) (ABIN7451635)

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-APC1 Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-APC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Alternative Name: APC1

Background: Background: Anaphase-promoting complex subunit 1(APC1) is a component of the anaphase-promoting complex (APC). The APC complex functions as an ubiquitin ligase and is responsible for the ubiquitination of securin and cyclin B and prompts the onset of anaphase and the exit from mitosis. The APC complex is composed of at least 11 APC components. APC1 is the largest of these subunits.

Gene ID: 64682

NCBI Accession: NP_073153

UniProt: Q9H1A4