ATG4B antibody (AA 350-400)

Catalog No. ABIN7451650

This Rabbit Polyclonal antibody specifically detects ATG4B in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for ATG4B antibody (AA 350-400) (ABIN7451650)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ATG4B Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-Atg4B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: Atg4B

Background: Background: Atg4B (ATG4 autophagy related 4 homolog B) is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes [taken from the Universal Protein Resource (UniProt) Q9Y4P1].

Gene ID: 23192

NCBI Accession: NP_037457

UniProt: Q9Y4P1

Pathways: Autophagy