BCAR3 antibody (AA 25-75)

Catalog No. ABIN7451660

Product Details anti-BCAR3 Antibody

Target: BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

Binding Specificity: AA 25-75

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-BCAR3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCAR3

Target: BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

Alternative Name: BCAR3 (BCAR3 Products)

Synonyms: NSP2 antibody, SH2D3B antibody, AI131758 antibody, AND-34 antibody, BCAR3 antibody, breast cancer anti-estrogen resistance 3 antibody, breast cancer anti-estrogen resistance 3 L homeolog antibody, BCAR3 antibody, Bcar3 antibody, bcar3 antibody, bcar3.L antibody

Background: Background: BCAR3 (breast cancer anti-estrogen resistance 3) was originally identified as a factor that confers resistance to anti-estrogens in breast cancer cells. BCAR3 contains a Ras-GEF domain and an SH2 domain. It is related to SHEP1 and NSP1 and is thought to also play a role as an adaptor protein that mediates integrin signaling to modulate cell adhesion and migration.

Gene ID: 8412

NCBI Accession: NP_003558

UniProt: O75815