BCOR antibody (AA 1705-1755)
Quick Overview for BCOR antibody (AA 1705-1755) (ABIN7539902)
Target
See all BCOR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1705-1755
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Purpose
- Rabbit anti-BCoR Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1705 and 1755
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- BCOR (BCL6 Co-Repressor (BCOR))
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Alternative Name
- BCoR
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Background
- Background: The BCL6 co-repressor (BCOR) was identified in a two-hybrid screen for factors that interact with the POZ domain of BCL6, a transcriptional repressor important to the immune response and B-cell development. BCOR also interacts with class I and II histone deacetylases and has recently been identified in a complexes with polycomb group proteins, RING1, RYBP, SNSC1, and RNF2, and the ubiquitin E3 ligase SKP1, and JHDM1B. Defects in BCOR are associated with oculo-facio-cardio-dental (OFCD) syndrome, a rare X-linked dominant disease that is fatal in males.
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Gene ID
- 54880
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UniProt
- Q6W2J9
Target
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