Beclin 1 antibody (AA 1-50)

Catalog No. ABIN7451663

The Rabbit Polyclonal anti-Beclin 1 antibody has been validated for WB and IP. It is suitable to detect Beclin 1 in samples from Human and Mouse.

Quick Overview for Beclin 1 antibody (AA 1-50) (ABIN7451663)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Beclin 1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Beclin 1 Antibody, Affinity Purified

Predicted Reactivity: Rat,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: Beclin 1

Background: Background: Beclin 1 was initially identified as a Bcl-2 interacting protein. Beclin 1 has been found to play a role in autophagy, the process whereby cellular structures, organelles, and intracellular pathogens undergo degradation. As an interacting protein of Bcl-2, beclin is able to influence Bcl-2 to function as an autophagy protein.

Gene ID: 8678

NCBI Accession: NP_003757

UniProt: Q14457

Pathways: Autophagy