GRF2 antibody (AA 375-425)

Catalog No. ABIN7451670

This anti-GRF2 antibody is a Rabbit Polyclonal antibody detecting GRF2 in WB and IP. Suitable for Human.

Quick Overview for GRF2 antibody (AA 375-425) (ABIN7451670)

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-GRF2 Antibody

Binding Specificity: AA 375-425

Purpose: Rabbit anti-C3G Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 375 and 425

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Alternative Name: C3G

Background: Background: CRK SH3-binding GNRP (C3G) is a guanine nucleotide exchange factor (GEF) that binds to the SH3 domain of CRK and GRB2/ASH and catalyzes the exchange of GDP for GTP on GTPases of the Ras family. C3G has been reported to be involved in signaling that mediates cell adhesion and migration.

Gene ID: 2889

NCBI Accession: NP_005303

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor