CDC7 antibody (AA 524-574)

Catalog No. ABIN7451693

The Rabbit Polyclonal anti-CDC7 antibody has been validated for WB and IP. It is suitable to detect CDC7 in samples from Human.

Quick Overview for CDC7 antibody (AA 524-574) (ABIN7451693)

Target: CDC7 (Cell Division Cycle 7 (CDC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CDC7 Antibody

Binding Specificity: AA 524-574

Purpose: Rabbit anti-CDC7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 524 and 574

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDC7

Target: CDC7 (Cell Division Cycle 7 (CDC7))

Alternative Name: CDC7

Background: Background: Cell division cycle 7-related protein kinase 7 (CDC7) is critical for the activation and firing of replication origins during S-phase. Cdc7 kinase activity is activated and regulated by Dbf4. Substrates of CDC7 include the MCM (mini-chromosome maintenance) proteins, DNA polymerase alpha, Cdc45, Orc4, geminin and SV40 T-antigen. CDC7 has also been implicated to play a role in the DNA damage response. Alternative names for CDC7 include,CDC7L1, hsCDC7, huCDC7, and Hsk1.

Gene ID: 8317

NCBI Accession: NP_003494

UniProt: O00311

Pathways: Mitotic G1-G1/S Phases, DNA Replication