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CIZ1 antibody (AA 325-375)

CIZ1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7451704
  • Target See all CIZ1 Antibodies
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-375
    Reactivity
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    • 1
    • 1
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CIZ1 antibody is un-conjugated
    Application
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Rabbit anti-CIZ1 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogen
    between AA 325 and 375
    Isotype
    IgG
    Top Product
    Discover our top product CIZ1 Primary Antibody
  • Application Notes

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    Alternative Name
    CIZ1 (CIZ1 Products)
    Synonyms
    LSFR1 antibody, NP94 antibody, ZNF356 antibody, CIZ1 antibody, 0610038H21Rik antibody, 2900056O04Rik antibody, ciz1 antibody, wu:fi12g11 antibody, wu:fi27d02 antibody, zgc:66467 antibody, CDKN1A interacting zinc finger protein 1 antibody, cip1-interacting zinc finger protein antibody, cdkn1a interacting zinc finger protein 1b antibody, CIZ1 antibody, LOC464765 antibody, Ciz1 antibody, ciz1b antibody
    Background
    Background: CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.
    Gene ID
    25792
    NCBI Accession
    NP_036259
    UniProt
    Q9ULV3
    Pathways
    Maintenance of Protein Location
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