DHX16 antibody (AA 991-1041)

Catalog No. ABIN7451736

Product Details anti-DHX16 Antibody

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Binding Specificity: AA 991-1041

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX16 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-DHX16 Antibody, Affinity Purified

Predicted Reactivity: Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 991 and 1041

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DHX16

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Alternative Name: DHX16 (DHX16 Products)

Synonyms: fa91b12 antibody, zgc:55590 antibody, wu:fa91b12 antibody, dbp2 antibody, ddx16 antibody, pro2014 antibody, prp2 antibody, prp8 antibody, prpf2 antibody, DHX16 antibody, DKFZp459L1130 antibody, DBP2 antibody, DDX16 antibody, PRO2014 antibody, PRP8 antibody, PRPF2 antibody, Prp2 antibody, 2410006N22Rik antibody, Ddx16 antibody, mKIAA0577 antibody, Dbp2 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 16 antibody, DEAH-box helicase 16 antibody, putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 antibody, dhx16 antibody, DHX16 antibody, LOC100637149 antibody, Dhx16 antibody

Background: Background: DHX16 is a member of the DEAH-box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH-box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DH16 was originally identified as DBP2 and discovered to be a functional homolog of the yeast RNA helicase and ATPase, Cdc28/Prp68. DHX16 appears to play a key role in nonsense-mediated mRNA decay (NMD) as well as rRNA processing.

Gene ID: 8449

NCBI Accession: NP_003578

UniProt: O60231