EIF3H antibody (AA 302-352)

Catalog No. ABIN7451759

The Rabbit Polyclonal anti-EIF3H antibody is suitable to detect EIF3H in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for EIF3H antibody (AA 302-352) (ABIN7451759)

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3H antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-EIF3H Antibody

Binding Specificity: AA 302-352

Purpose: Rabbit anti-eIF3H/EIF3S3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 302 and 352

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EIF3H

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Alternative Name: eIF3H/EIF3S3

Background: Background: Eukaryotic initiation factor 3 subunit H (eIF3H) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3H is a non-conserved subunit and part of the functional core of eIF3. It may function to stabilize the eIF3 complex and stimulate protein synthesis. Many cancer cell lines have been shown to express high levels of eIF3H, and it may have an oncogenic role in colorectal cancer susceptibility.

Gene ID: 8667

NCBI Accession: NP_003747

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization