EIF3K antibody (AA 168-218)
Quick Overview for EIF3K antibody (AA 168-218) (ABIN7451760)
Target
See all EIF3K AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 168-218
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Purpose
- Rabbit anti-eIF3K/EIF3S12 Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Bovine
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Purification
- Affinity Purified
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Immunogen
- between AA 168 and 218
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
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Alternative Name
- eIF3K/EIF3S12
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Background
- Background: Eukaryotic initiation factor 3 subunit K (eIf3K) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3 has been found to localize to both the nucleus and cytoplasm. In the cytoplasm, eIf3K associates with keratin 18 in intermediate filaments of epithelial cells and may have an apoptosis-promoting function. It also has been shown to interact with cyclin D3.
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Gene ID
- 27335
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NCBI Accession
- NP_037366
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UniProt
- Q9UBQ5
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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