NDC80 antibody (C-Term)

Catalog No. ABIN7451806

This Rabbit Polyclonal antibody specifically detects NDC80 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for NDC80 antibody (C-Term) (ABIN7451806)

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDC80 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NDC80 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-HEC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 600 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Alternative Name: HEC1

Background: Background: HEC1 (highly expressed in cancer 1) is a component of the kinetochore-associated NDC80 complex that is essential for maintaining kinetochore integrity, proper chromosome segregation, and spindle-checkpoint signaling. HEC1 has been shown to be required for the organization of kinetochore microtubule attachment sites.

Gene ID: 10403

NCBI Accession: NP_006092

UniProt: O14777

Pathways: Maintenance of Protein Location