NFRKB antibody (AA 1025-1075)
Quick Overview for NFRKB antibody (AA 1025-1075) (ABIN7451893)
Target
See all NFRKB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1025-1075
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Purpose
- Rabbit anti-NFRKB Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1025 and 1075
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))
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Alternative Name
- NFRKB
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Background
- Background: NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.
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Gene ID
- 4798
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UniProt
- Q6P4R8
Target
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