NFRKB antibody (AA 1249-1299)

Catalog No. ABIN7452377

Product Details anti-NFRKB Antibody

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Binding Specificity: AA 1249-1299

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFRKB antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-NFRKB Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1249 and 1299

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NFRKB antibody ABIN7451893.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NFRKB

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Alternative Name: NFRKB (NFRKB Products)

Synonyms: nfrkb antibody, MGC75871 antibody, NFRKB antibody, A530090G11Rik antibody, INO80G antibody, nuclear factor related to kappaB binding protein antibody, amyloid beta precursor like protein 2 antibody, nuclear factor related to kappa B binding protein antibody, nfrkb antibody, NFRKB antibody, APLP2 antibody, Nfrkb antibody

Background: Background: NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.

Gene ID: 4798

UniProt: Q6P4R8