p115-RhoGEF (AA 275-325) antibody

Catalog No. ABIN7451919

The Rabbit Polyclonal anti-p115-RhoGEF antibody (ABIN7451919) specifically detects p115-RhoGEF in IP and WB. The antibody is reactive with Human samples.

Quick Overview for p115-RhoGEF (AA 275-325) antibody (ABIN7451919)

Target: p115-RhoGEF

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP), Western Blotting (WB)

Product Details

Binding Specificity: AA 275-325

Purpose: Rabbit anti-p115-RhoGEF Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 275 and 325

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: p115-RhoGEF

Background: Background: P115-RhoGEF plays a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. P115-RhoGEF acts as a GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. The gene name for p115-RhoGEF is ARHGEF1 [taken from the Universal Protein Resource (UniProt) Q92888].

Gene ID: 9138

NCBI Accession: NP_004697

UniProt: Q92888