PDE8A antibody (AA 779-829)

Catalog No. ABIN7451946

This anti-PDE8A antibody is a Rabbit Polyclonal antibody detecting PDE8A in WB and IP. Suitable for Human.

Quick Overview for PDE8A antibody (AA 779-829) (ABIN7451946)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PDE8A Antibody

Binding Specificity: AA 779-829

Purpose: Rabbit anti-PDE8A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 779 and 829

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background: Background: Phosphodiesterase 8A (PDE8A) is a member of a large family of phosphodiesterases (PDEs) that regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction [taken from NCBI Entrez Gene (Gene ID: 5151)].

Gene ID: 5151

NCBI Accession: NP_002596

UniProt: O60658

Pathways: cAMP Metabolic Process