PTPN12 antibody (AA 375-425)

Catalog No. ABIN7451987

The Rabbit Polyclonal anti-PTPN12 antibody has been validated for WB and IP. It is suitable to detect PTPN12 in samples from Human.

Quick Overview for PTPN12 antibody (AA 375-425) (ABIN7451987)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN12 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PTPN12 Antibody

Binding Specificity: AA 375-425

Purpose: Rabbit anti-PTPN12 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 375 and 425

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Alternative Name: PTPN12

Background: Background: PTPN12 is a cytosolic protein tyrosine phosphatase (PTP) that contains a C-terminal PEST motif and plays an important role in cytoskeletal organization, immune cell activation, apoptosis, and embryonic development. PTPN12 appears to contribute to these cellular processes through its interaction with a variety of signaling and cytoskeletal-associated proteins. The recent discovery that PTPN12 is modulated by caspase-3 cleavage has led to the analysis of the role of PTPN12 and other PTPs as regulators of apoptosis.

Gene ID: 5782

NCBI Accession: NP_002826

UniProt: Q05209