SRA1 antibody (C-Term)

Catalog No. ABIN7452064

This Rabbit Polyclonal antibody specifically detects SRA1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SRA1 antibody (C-Term) (ABIN7452064)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SRA1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-SRA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 180 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: SRA

Background: Background: Steroid receptor RNA activator 1 (SRA) was originally identified as a functional non-coding RNA that has been shown to be a coactivator of steroid receptors for androgens (AR), estrogens (ER), glucocorticoids, and progestins (PR). SRA exists in ribonucleoprotein complexes with steroid receptor coactivators (SRCs) and steroid receptors and may modulate transcriptional specificity. A 236 amino-acid protein encoded by an SRA-RNA isoform has also been identified. The SRA protein (SRAP) is widely expressed in breast cancer cell lines and breast cancer and has been demonstrated to modify the activity of the estrogen receptor.

Gene ID: 10011

NCBI Accession: NP_001030312

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development